The countdown is on for online and retail sports betting in Missouri. The state will go live on December 1, 2025. This debut will make both mobile and in-person betting legal across the Show-Me State. Once live, you will see all the big markets: moneylines, point spreads, totals, player props, futures, and live, in-game wagers.
The timing could not be better. Legal betting launches right in the middle of a heavy sports month. Read on to find out more about the available betting opportunities you can leverage from day one.
What bettors can legally wager on from day one?
When sports betting in Missouri launches, you will be able to bet on major professional sports like the NFL, NBA, and NHL. You will also have unrestricted access to bet on college football and other college sports.
The Missouri betting scene is also welcoming futures bets. This means that you will be able to wager on who will win a league or tournament. Popular betting markets will be available for plates. The MLB Royals are out of season in December. However, their win-total futures and similar bets could still be available.
Opening-week games you can bet immediately after launch
Once sports betting in Missouri goes live on December 1, 2025, bettors can place legal wagers on real games from day one.
The first big event is Monday Night Football. Here, the New York Giants play the New England Patriots at 8:15 p.m. ET. This game will be available on licensed Missouri betting apps and retail books.
Later in the same week, on Sunday, December 7, Missouri fans can bet on the Kansas City Chiefs at home when they host the Houston Texans in primetime. This will likely be the first hometown NFL game. Many residents will bet on this through Missouri sportsbooks.
Early December also has other notable NFL games that matter for playoff races. Examples include Packers vs Bears and Chargers vs Cowboys. This match gives you more betting options.
The NBA schedule adds more action. On December 9 and 10, the NBA Cup quarterfinals are expected to kick off. Users will see quick access to same-game parlays, player props, spreads, and totals inside legal sports betting apps in Missouri as soon as the market opens.
Hockey angle: Missouri bettors get a Blues game immediately
When sports betting in Missouri launches on December 1, hockey will be one of the first markets available. The St. Louis Blues play at home that same night against the Anaheim Ducks. This game gives fans an instant in-state wager through legal Missouri sportsbooks or Missouri betting apps.
A few days later, the Blues travel to face the Boston Bruins. This is another high-profile national game. Hockey markets will include full-game lines, period bets, shots-on-goal props, and goal-scorer bets. Later in December, neutral bettors can follow major matchups like Panthers vs Oilers for wider NHL options.
December college schedule adds more volume later in the month
College sports will also boost sports betting in Missouri later in December. The new 12-team College Football Playoff begins with first-round games on December 19 and 20. Quarterfinal bowls such as the Cotton Bowl follow on December 31. Bowl season starts in mid-December, and college basketball adds more markets through non-conference and conference play on legal Missouri betting apps.
Closing tips
No doubt, the Missouri sports betting launch lands in a busy sports month. Be prepared. Pre-register now with licensed Missouri betting apps. Confirm that the operator is approved to offer legal sports betting in Missouri. Compare odds, read promo rules, and set limits before you start placing bets.