University of Colorado quarterback Shedeur Sanders, once an odds-on favorite to be a top-5 2025 NFL Draft pick, wasn’t selected Thursday among the 32 picks in the first round.  

Now, as one of the top prospects still available, Sanders is one of the favorites to be the first player off the board in Round 2 Friday night when the draft resumes at 7 p.m. ET.

Below we examine Sanders’ updated draft odds at a few of the flagship sports betting sites. 

The 2025 NFL Draft kicks off with the first round Thursday night in Green Bay, Wis.

Rounds 2-7 follow Friday and Saturday in the premier event of the NFL offseason.

Draft betting markets are more popular than ever, and first-time customers using BetMGM Sportsbook bonus code PLAYDEAL to wager on the event can collect a bonus of up to $1,500.

The 2025 NFL Draft goes live Thursday night with the first round from Green Bay, Wis.

Rounds 2 and 3 follow Friday and Rounds 4-7 conclude the proceedings Saturday.

With sportsbooks offering more draft markets than ever, it’s an ideal event for sports betting. 

The NFL draft is set to get underway Thursday night, and Caesars Sportsbook promo code PLAYRACEDYW will help anyone interested bettor win double on up to 10 subsequent bets.

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The NFL will return to the national TV stage the first time since the Super Bowl with the NFL draft starting Thursday, and our Fanatics Sportsbook promo code is the key to the betting public unlocking up to $1,000 in bonus bets.

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As the countdown to Thursday night's first round of the 2025 NFL Draft continues, the futures of notable prospects such as Shedeur Sanders and Tetairoa McMillan are just as volatile as their betting odds.

Welcome to NFL Draft week with the three-day, seven-round selection process getting underway at 8 p.m. ET Thursday in Green Bay, Wis.

Draft betting markets are more popular than ever with sportsbooks offering odds ranging from which players will be selected with each of the top-10 picks to the player position each team will draft with their top selection to over/under totals on how many players at a position or representing a college conference will be selected in the first round.

The dust has settled following the main wave of NFL free agency and the draft looms in three weeks.

So how has that impacted futures odds to win Super Bowl 60, scheduled next Feb. 8 in Santa Clara, Calif?

The short answer is not much, at least at the top of the leading online sportsbooks’ odds boards. The top five favorites to win Super Bowl LX remain, in order, the defending-champion Philadelphia Eagles, runner-up Kansas City Chiefs, Baltimore Ravens, Buffalo Bills and Detroit Lions.

The coming and going of the 2025 NFL Scouting Combine confirmed what was widely believed around the sports world, which is that University of Miami quarterback Cam Ward is the clear leader in NFL Draft first pick sports betting odds.

While green and white Philadelphia Eagles confetti still is being swept up in New Orleans, oddsmakers and bettors have turned their focus to the 2025 NFL season and Super Bowl 60.

Below, we take a look at the futures odds and early favorites to hoist the Lombardi Trophy next Feb. 8 in Santa Clara, Calif.